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rdf:type |
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|
lifeskim:mentions |
|
|
pubmed:issue |
2
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pubmed:dateCreated |
1982-12-2
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pubmed:abstractText |
Duck hepatitis B virus, a DNA virus closely related to human hepatitis B virus, was studied in infected duck liver. Subviral particles resembling the viral nucleocapsid cores were isolated from persistently infected liver and shown to have a DNA polymerase activity that utilizes an endogenous template and synthesizes both plus- and minus-strand viral DNA. Synthesis of the viral minus-strand DNA utilized an RNA template that was degraded as it was copied. Viral plus-strand synthesis occurred on the completed minus-strand DNA. A pathway for the replication of the DNA genome of hepatitis B-like viruses by reverse transcription of an RNA intermediate is proposed.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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|
pubmed:issn |
0092-8674
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
29
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|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
403-15
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6180831-Animals,
pubmed-meshheading:6180831-DNA, Viral,
pubmed-meshheading:6180831-DNA-Directed DNA Polymerase,
pubmed-meshheading:6180831-Dactinomycin,
pubmed-meshheading:6180831-Deoxyribonucleases,
pubmed-meshheading:6180831-Ducks,
pubmed-meshheading:6180831-Genes, Viral,
pubmed-meshheading:6180831-Hepatitis B virus,
pubmed-meshheading:6180831-Liver,
pubmed-meshheading:6180831-RNA, Viral,
pubmed-meshheading:6180831-RNA-Directed DNA Polymerase,
pubmed-meshheading:6180831-Ribonucleases,
pubmed-meshheading:6180831-Virus Replication
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pubmed:year |
1982
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|
pubmed:articleTitle |
Replication of the genome of a hepatitis B--like virus by reverse transcription of an RNA intermediate.
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
