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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1982-10-29
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pubmed:abstractText |
Parameters of RNA synthesis were measured after a temperature upshift in a pair of Escherichia coli B/r strains that are isogenic except for having relA and relA+ loci, to examine the cause for a reported anomaly in the correlation between guanosine tetraphosphate (ppGpp) and stable RNA (rRNA, tRNA) synthesis under such conditions. Two main results were: (i) the specific stable RNA gene activity (stable RNA per total RNA synthesis) correlated in the conventionally expected fashion with the level of ppGpp but was obscured by a nonspecific increase in the RNA chain elongation rate due to the higher temperature; (ii) the temperature upshift caused a transient reduction in the RNA polymerase activity (transcribing per total enzyme) that accounts for the previously observed oscillating RNA synthesis rate after a temperature shift.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-1092659,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-1108019,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-13611202,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-13916843,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-14907713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-149109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-320174,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-324975,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-326415,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-332163,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-350413,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-4573841,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-4885263,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-4937124,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-6154044,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-6155374,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-6161933,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-6164923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-6174501,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-6175615,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-6178724,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-787760,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6179925-8211
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Directed RNA Polymerases,
http://linkedlifedata.com/resource/pubmed/chemical/Guanosine Tetraphosphate,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Ribosomal,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Transfer
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0021-9193
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
151
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1425-32
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6179925-Bacterial Proteins,
pubmed-meshheading:6179925-DNA-Directed RNA Polymerases,
pubmed-meshheading:6179925-Escherichia coli,
pubmed-meshheading:6179925-Guanosine Tetraphosphate,
pubmed-meshheading:6179925-Kinetics,
pubmed-meshheading:6179925-RNA, Bacterial,
pubmed-meshheading:6179925-RNA, Messenger,
pubmed-meshheading:6179925-RNA, Ribosomal,
pubmed-meshheading:6179925-RNA, Transfer,
pubmed-meshheading:6179925-Temperature
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pubmed:year |
1982
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pubmed:articleTitle |
Control of RNA synthesis in Escherichia coli after a shift to higher temperature.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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