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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0003241,
umls-concept:C0006826,
umls-concept:C0024141,
umls-concept:C0024264,
umls-concept:C0030705,
umls-concept:C0127400,
umls-concept:C0205307,
umls-concept:C0205359,
umls-concept:C0596402,
umls-concept:C0681850,
umls-concept:C0851827,
umls-concept:C1550501,
umls-concept:C1701901,
umls-concept:C1706203,
umls-concept:C2349001,
umls-concept:C2697811
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pubmed:issue |
3
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pubmed:dateCreated |
1979-4-28
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pubmed:abstractText |
Antibody dependent and spontaneous lymphocyte mediated cytotoxicity was studied in healthy subjects and patients with systemic lupus erythematosus and metastatic tumours. The purified peripheral blood lymphocytes of healthy subjects exerted a similar cytotoxic activity on allogeneic K-562 and xenogeneic chicken erythrocyte targets in the antibody dependent and spontaneous lymphocyte mediated cytotoxicity tests. There was a stronger correlation between the cytotoxicity measured in the two allogeneic assays than between allogeneic and xenogeneic tests. Allogeneic systems using K-562 targets were more sensitive to changes in cytotoxic activity in systemic lupus erythematosus and metastatic tumours than was the xenogeneic chicken erythrocyte assay.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0001-5989
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
123-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:617926-Antibody-Dependent Cell Cytotoxicity,
pubmed-meshheading:617926-Breast Neoplasms,
pubmed-meshheading:617926-Humans,
pubmed-meshheading:617926-Intestinal Neoplasms,
pubmed-meshheading:617926-Lung Neoplasms,
pubmed-meshheading:617926-Lupus Erythematosus, Systemic,
pubmed-meshheading:617926-Lymphocytes,
pubmed-meshheading:617926-Neoplasm Metastasis,
pubmed-meshheading:617926-Neoplasms,
pubmed-meshheading:617926-Tongue Neoplasms
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pubmed:year |
1977
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pubmed:articleTitle |
Antibody dependent and spontaneous lymphocyte mediated cytotoxicity in normal subjects, patients with SLE, and malignancies.
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pubmed:publicationType |
Journal Article
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