Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-7-22
pubmed:abstractText
A viral inhibitor displaying the main properties of a type 1 (alpha or beta) interferon was found in intestine and serum of diarrheic newborn calves following oral administration of bovine rotavirus. Other internal organs examined 24 hours after infection all contained appreciable amounts of interferon. A kinetic study performed in ileum and serum of a one day-old calf showed a good time correspondence between peak levels of virus multiplication in the gut, intestinal interferon, and systemic interferon. In the same experiment, a two week-old calf was refractory to the disease, developing much delayed and weaker productions of both virus and interferon, when compared to the newborn calf. Therefore, the enhanced susceptibility of the newborn calf to rotavirus induced diarrhea is not related to a deficiency in interferon synthesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0003-4193
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
85-91
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Interferon activity in rotavirus infected newborn calves.
pubmed:publicationType
Journal Article