Linked Life Data

6174701

Source:http://linkedlifedata.com/resource/pubmed/id/6174701

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-5-21
pubmed:abstractText
Lesion-induced degeneration was combined with the retrograde transport of horseradish peroxidase (HRP) to examine the thalamocortical and other synaptical relationships of corticothalamic projection cells in mouse SmI cortex. Injections containing 40% HRP were placed in the ventrobasal thalamus and the next day, electrolytic lesions were made of the injection site. About four days later, the animals were perfused with aldehydes and SmI cortex ipsilateral to the injection and lesion sites was tissue chopped and reacted for HRP. The somata of HRP-filled corticothalamic cells in SmI cortex had diameters of about 10 micrometers and occurred in the upper half of layer VI and in the lower half of layer V; their apical dendrites usually terminated within or just below layer IV, but in some instances, extended nearly to the pial surface. Reconstructions of serial thin sections through the layer IV portions of the apical dendrites of seven well-labelled corticothalamic cells showed them to form 7 to 20% of their synapses with degenerating thalamocortical axon terminals. In contrast, the proportion of thalamocortical synapses formed by the layer IV dendrites of corticostriatal (Hersch & White, in preparation) and corticocortical (White & Hersch, 1981) projection cells ranges from 0.3 to 0.9% and from 1.5 to 6.8%, respectively. We interpret these findings to indicate that pyramidal cell dendrites are specified to form characteristic proportions of thalamocortical synapses.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0300-4864
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
137-57
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
A quantitative study of thalamocortical and other synapses involving the apical dendrites of corticothalamic projection cells in mouse SmI cortex.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.