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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1982-5-21
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pubmed:abstractText |
Sixty-one patients with epidermoid carcinoma of the esophagus have been treated with a three drug combination of cisplatin, vindesine, and bleomycin. Of 53 patients currently evaluable for response, 29 (55%) have had partial remissions: 7/16 with metastatic, and 22/37 with local-regional disease. The median duration of response in metastatic patients is eight months. Of 28 patients treated preoperatively, 23 (82%) had resectable disease. The major toxicities seen were nephrotoxicity and myelosuppression. Cisplatin, vindesine and bleomycin is an effective combination in the treatment of esophageal carcinoma. Effects on long-term survival cannot yet be evaluated.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1174-7
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:6174199-Acute Kidney Injury,
pubmed-meshheading:6174199-Bleomycin,
pubmed-meshheading:6174199-Carcinoma, Squamous Cell,
pubmed-meshheading:6174199-Cisplatin,
pubmed-meshheading:6174199-Drug Administration Schedule,
pubmed-meshheading:6174199-Drug Therapy, Combination,
pubmed-meshheading:6174199-Esophageal Neoplasms,
pubmed-meshheading:6174199-Female,
pubmed-meshheading:6174199-Humans,
pubmed-meshheading:6174199-Leukopenia,
pubmed-meshheading:6174199-Male,
pubmed-meshheading:6174199-Vinblastine,
pubmed-meshheading:6174199-Vindesine
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pubmed:year |
1982
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pubmed:articleTitle |
Combination chemotherapy of esophageal carcinoma using cisplatin, vindesine, and bleomycin.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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