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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8266
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pubmed:dateCreated |
1982-4-12
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pubmed:abstractText |
Atopic asthmatics who produce allergen-specific IgE antibodies develop an immediate reaction to bronchial provocation; those who produce allergen-specific IgG4 antibodies develop a delayed response; and those who produce both classes of antibody against the same allergen exhibit a dual response. Individual patients showed a variable immune response to different allergens, producing bot classes of antibody against one, but only IgE or IgG4 against others. These findings suggest that allergen-specific IgG4 antibodies are important in the production of severe asthma and probably atopic eczema as well.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0140-6736
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
254-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6173557-Adolescent,
pubmed-meshheading:6173557-Adult,
pubmed-meshheading:6173557-Allergens,
pubmed-meshheading:6173557-Asthma,
pubmed-meshheading:6173557-Bronchial Provocation Tests,
pubmed-meshheading:6173557-Child,
pubmed-meshheading:6173557-Dust,
pubmed-meshheading:6173557-Epitopes,
pubmed-meshheading:6173557-Humans,
pubmed-meshheading:6173557-Hypersensitivity, Delayed,
pubmed-meshheading:6173557-Immunoglobulin E,
pubmed-meshheading:6173557-Immunoglobulin G,
pubmed-meshheading:6173557-Middle Aged,
pubmed-meshheading:6173557-Pollen
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pubmed:year |
1982
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pubmed:articleTitle |
Bronchial provocation tests in atopic patients with allergen-specific IgG4 antibodies.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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