rdf:type |
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0038856,
umls-concept:C0071310,
umls-concept:C0185117,
umls-concept:C0332120,
umls-concept:C0439851,
umls-concept:C0522224,
umls-concept:C1314939,
umls-concept:C1552596,
umls-concept:C1947931,
umls-concept:C2911684
|
pubmed:issue |
3
|
pubmed:dateCreated |
1982-4-20
|
pubmed:abstractText |
Prior treatment (priming) with a subimmunogenic dose of type III pneumococcal polysaccharide results in the development of an antigen-specific state of unresponsiveness termed low-dose paralysis. Such unresponsiveness can be transferred by spleen cells obtained from mice within 5 to 24 hr after priming; the suppressive activity of transferred cells is abolished by treatment with monoclonal anti-Thy-1.2 antibody and complement. These findings show clearly that low-dose paralysis is mediated by T suppressor cells.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0022-1767
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
128
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1059-62
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:6173416-Animals,
pubmed-meshheading:6173416-Antibody-Producing Cells,
pubmed-meshheading:6173416-Dose-Response Relationship, Immunologic,
pubmed-meshheading:6173416-Epitopes,
pubmed-meshheading:6173416-Female,
pubmed-meshheading:6173416-Immune Tolerance,
pubmed-meshheading:6173416-Immunity, Cellular,
pubmed-meshheading:6173416-Kinetics,
pubmed-meshheading:6173416-Mice,
pubmed-meshheading:6173416-Mice, Inbred BALB C,
pubmed-meshheading:6173416-Paralysis,
pubmed-meshheading:6173416-Polysaccharides, Bacterial,
pubmed-meshheading:6173416-Streptococcus pneumoniae,
pubmed-meshheading:6173416-T-Lymphocytes,
pubmed-meshheading:6173416-T-Lymphocytes, Regulatory,
pubmed-meshheading:6173416-Trinitrobenzenes
|
pubmed:year |
1982
|
pubmed:articleTitle |
Direct evidence for the involvement of T suppressor cells in the expression of low-dose paralysis to type III pneumococcal polysaccharide.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|