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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
6
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pubmed:dateCreated |
1982-1-28
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pubmed:abstractText |
The existence of a helper T cell cooperating with cytolytic T lymphocytes (CTL) in cell-mediated anti-tumor responses specific for the virus-induced FMR antigens can be demonstrated by using unprimed thymocytes as CTL precursors and in vivo primed irradiated spleen cells as helper. The helper T cells express Thy-1.2 and Lyt-1.2 antigens at their surface, but not Lyt-2.2. The helper function required the presence of macrophages to be detected, is antigen specific, and appears unusually radiosensitive compared with previously described helper T cell function.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0022-1767
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
127
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2291-5
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:6170695-Animals,
pubmed-meshheading:6170695-Antigens, Viral,
pubmed-meshheading:6170695-Cytotoxicity, Immunologic,
pubmed-meshheading:6170695-Epitopes,
pubmed-meshheading:6170695-Friend murine leukemia virus,
pubmed-meshheading:6170695-Interleukin-2,
pubmed-meshheading:6170695-Killer Cells, Natural,
pubmed-meshheading:6170695-Leukemia, Experimental,
pubmed-meshheading:6170695-Macrophages,
pubmed-meshheading:6170695-Mice,
pubmed-meshheading:6170695-Mice, Inbred BALB C,
pubmed-meshheading:6170695-Mice, Inbred C57BL,
pubmed-meshheading:6170695-Moloney murine leukemia virus,
pubmed-meshheading:6170695-Phenotype,
pubmed-meshheading:6170695-Rauscher Virus,
pubmed-meshheading:6170695-Retroviridae,
pubmed-meshheading:6170695-Spleen,
pubmed-meshheading:6170695-T-Lymphocytes
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pubmed:year |
1981
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pubmed:articleTitle |
Accessory cells in the in vitro generation of type C virus-specific T killer lymphocytes. II. Demonstration of a T helper cell in the spleen of in vivo primed mice.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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