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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
|
| pubmed:dateCreated |
1981-12-21
|
| pubmed:abstractText |
Stroma-free hemoglobin solutions present some drawbacks when used as blood substitutes, essentially because the hemoprotein has a low vascular retention, due to its small hydrodynamic volume. Covalent coupling of the protein with dextran derivatives artificially increases its size and affords polymeric conjugates whose oxygen-binding properties (Barcroft's curve, Hill coefficient) depend on the molecular weight.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0014-4754
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
37
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
884-6
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:6169540-Chemical Phenomena,
pubmed-meshheading:6169540-Chemistry,
pubmed-meshheading:6169540-Dextrans,
pubmed-meshheading:6169540-Hemoglobins,
pubmed-meshheading:6169540-Humans,
pubmed-meshheading:6169540-Molecular Weight,
pubmed-meshheading:6169540-Oxidation-Reduction,
pubmed-meshheading:6169540-Oxygen
|
| pubmed:year |
1981
|
| pubmed:articleTitle |
Preparation and oxygen binding properties of soluble covalent hemoglobin-dextran conjugates.
|
| pubmed:publicationType |
Journal Article
|