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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1981-11-22
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pubmed:abstractText |
An examination of the pattern of outflow of radioactivity in sciatic nerves was made at times from 1 to 82 days in the rat and up to 132 days in the cat after injecting the L5 and L7 dorsal root ganglia, respectively, with 3H-leucine. Slow waves moving at a rate of 1-2 mm/day were looked for on the basis of their reported presence in the motor fibers of the rat. A consistent pattern of slow waves was not seen in the cat or rat sensory fibers of the sciatic nerves nor was evidence of a slow wave found in the cat dorsal columns. Irregularities in the pattern of outflow which at times appeared as "waves" did so in an irregular fashion, a pattern inconsistent with a steady progression of slow waves in the fibers. The decrease of radioactivity appearing first near the ganglia helps create the impression of a wave along with irregular decreases in the overall levels of radio-activity with time. The results were explained on the basis of the unitary hypothesis. The labeled components are considered to be moved down the fiber by the fast transport mechanism, those components dropping off locally in the fibers early on, constituting the slow wave. As those components turn over locally in the various organelles of fiber and are further redistributed, they may at times give rise to what appears as waves.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-3034
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
441-53
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6168741-Animals,
pubmed-meshheading:6168741-Axonal Transport,
pubmed-meshheading:6168741-Cats,
pubmed-meshheading:6168741-Electric Conductivity,
pubmed-meshheading:6168741-Ganglia, Spinal,
pubmed-meshheading:6168741-Kinetics,
pubmed-meshheading:6168741-Leucine,
pubmed-meshheading:6168741-Nerve Tissue Proteins,
pubmed-meshheading:6168741-Sciatic Nerve,
pubmed-meshheading:6168741-Tritium
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pubmed:year |
1981
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pubmed:articleTitle |
Patterns of slow transport in sensory nerves.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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