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pubmed:abstractText |
The effect of intermittent normobaric hypoxia on nucleic acid and protein synthesis of guinea-pig heart was studied. De novo synthesis of purine nucleotides, of RNA and DNA, as well as RNA polymerase activities and protein synthesis, increased in the heart right ventricles of hypoxic animals compared to the controls. These results suggest an activation of cellular genetic apparatus with an increase of nucleic acid and protein syntheses during the compensatory processes following hypoxia.
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