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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1981-7-9
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pubmed:abstractText |
The serum, cerebrospinal (CSF) and brain of a patient (NAG) affected with multiple sclerosis (MS) were examined for measles antibodies with CF and HI techniques, and the kappa-lambda light chain ratios of all samples available were evaluated, kappa-lambda populations of the matched serum, CSF and brain specimens were all lambda-predominant and in agreement with each other; the light chain distribution f the brain specimens confirmed previous findings [3]. Only the serum immunoglobulins showed significant measles antibody titers, but slightly increased measles antibody titers were also observed in ventricular plaques. The amount of immunoglobulin G (IgG) synthesized per day by the central nervous system (CNS) was estimated. The IgG synthesis in CNS NAG (11.6 mg/day) was above the upper limit of the normal range (3.3 mg/day), but apparently there was no positive correlation between the intracerebral IgG synthesis and specific anti-measles IgG.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin Light Chains,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin kappa-Chains,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin lambda-Chains
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pubmed:status |
MEDLINE
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pubmed:issn |
0340-5354
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
225
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
135-43
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:6164764-Adult,
pubmed-meshheading:6164764-Antibodies, Viral,
pubmed-meshheading:6164764-Brain,
pubmed-meshheading:6164764-Electrophoresis, Agar Gel,
pubmed-meshheading:6164764-Female,
pubmed-meshheading:6164764-Humans,
pubmed-meshheading:6164764-Immunoglobulin G,
pubmed-meshheading:6164764-Immunoglobulin Light Chains,
pubmed-meshheading:6164764-Immunoglobulin kappa-Chains,
pubmed-meshheading:6164764-Immunoglobulin lambda-Chains,
pubmed-meshheading:6164764-Measles,
pubmed-meshheading:6164764-Multiple Sclerosis
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pubmed:year |
1981
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pubmed:articleTitle |
Measles antibodies, kappa-lambda light chain distribution and immunoglobulins in serum, cerebrospinal fluid and brain of a patient affected with multiple sclerosis.
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pubmed:publicationType |
Journal Article,
Case Reports
|