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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1981-5-28
|
| pubmed:abstractText |
The National Institute for Occupational Safety and Health (NIOSH) investigated the health effects of chronic exposure to low concentrations of carbon monoxide by conducting a historical prospective cohort study of mortality patterns among 1,558 white male motor vehicle examiners who were employed in New Jersey for a minimum of 6 months between 1944 and 1973. Industrial hygiene surveys indicated that the examiners were exposed to carbon monoxide at a time-weighted average (TWA) of 10-24 ppm; the exposure level recommended by NIOSH is 35 ppm TWA. A modified life table technique was used to calculate cause-specific expected deaths for the cohort adjusted for age and calendar time periods. The expected deaths were compared to the number of observed deaths through August 1973. The cohort demonstrated a slight overall increase in cardiovascular disease deaths (124 observed vs. 118.4 expected), but a more pronounced excess was observed within the first 10 yr. following employment (28 observed vs. 20.9 expected). A statistically significant excess of cancer mortality was found for motor vehicle examiners after 30 yr latency (13 observed vs. 6.9 expected, P < 0.5); this excess, however, was not confined to any particular organ site. The number of deaths due to accidents was significantly lower than expected (8 observed vs. 19.6 expected, P < .01).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0003-9896
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
36
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
59-65
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6163400-Air Pollutants,
pubmed-meshheading:6163400-Air Pollutants, Occupational,
pubmed-meshheading:6163400-Carbon Monoxide,
pubmed-meshheading:6163400-Carbon Monoxide Poisoning,
pubmed-meshheading:6163400-Cardiovascular Diseases,
pubmed-meshheading:6163400-Humans,
pubmed-meshheading:6163400-Male,
pubmed-meshheading:6163400-Neoplasms,
pubmed-meshheading:6163400-New Jersey,
pubmed-meshheading:6163400-Occupational Diseases,
pubmed-meshheading:6163400-Prospective Studies,
pubmed-meshheading:6163400-Vehicle Emissions
|
| pubmed:articleTitle |
Exposure of motor vehicle examiners to carbon monoxide: a historical prospective mortality study.
|
| pubmed:publicationType |
Journal Article
|