Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1981-5-26
pubmed:abstractText
To investigate the usefulness of regional response to post-extrasystolic potentiation as a predictor of left ventricular viability in patients with coronary artery disease, 46 patients underwent calibrated biplane left ventricular cineangiography during which a single, timed ventricular premature contraction was introduced. Results: Of 758 normal or hypokinetic segments, 486 (64.1%) showed a positive response to post-extrasystolic potentiation. Of 116 akinetic or dyskinetic segments, only 51 (43.9%) showed a positive response to post-extrasystolic potentiation (P less than 0.001). Because akinetic or dyskinetic areas would not be expected to respond to post-extrasystolic potentiation based on animal laboratory data, alternative explanations were sought to explain such positive response in man. Analysis of percent change in chord length of normal or hypokinetic segments adjacent to akinetic or dyskinetic segments that did or did not respond to post-extrasystolic potentiation revealed (10.2% +/- 1.2%) vs (1.3% +/- 0.7%) improvement, respectively (P less than 0.001) (mean +/- SE). Conclusion: Passive rather than active events may be responsible for "improved" regional wall motion following post-extrasystolic potentiation in akinetic or dyskinetic regions. If unrecognized, these factors may lead to improper interpretation of "intervention ventriculography" utilizing post-extrasystolic potentiation.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0098-6569
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
373-86
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Limitations of post-extrasystolic potentiation in assessing regional myocardial viability in man.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't