Linked Life Data

6160806

Source:http://linkedlifedata.com/resource/pubmed/id/6160806

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1981-2-19
pubmed:abstractText
It was shown for the first time that isoprinosine has an antiviral effect in treatment of experimental forest-spring encephalitis. The combined use of isoprinosine with mouse interferon in treatment of the infected albino mice potentiated antiviral effect as compared to the effect of substances used alone. In addition, the combined use of isoprinosine and interferon inductor in minimum nontoxic amounts resulted in a 4--8 fold increase in the titers of the serum interferon and a statistically significant increase in the mouse resistance to the viral infection. It was found that the efficacy of the combined use of isoprinosine and mouse interferon or interferon inductor increased, when the interval between the drug administrations was prolonged up to 24 hours. The maximum effect providing 75 per cent protection of the animals from the viral infection and an increase in the average life span of the mice from 7.9 to 17.4 days was observed with the combined use of isoprinosine and interferon inductor.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0003-5637
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
854-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
[Combined use of isoprinosine and an interferon inducer in experimental viral infection].
pubmed:publicationType
Journal Article, English Abstract