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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1981-2-24
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pubmed:abstractText |
The occurrence of intestinal metaplasia with colonic-type sulphomucins: (abbreviated: s-IM or s-positive IM) in the gastric mucosa was studied in 125 patients with gastric carcinoma (GCA), 62 patients with pernicious anemia (PA), 301 and 183 first-degree relatives of GCA and PA patients, 406 outpatients and in 358 controls matched from a large population sample. The sulphomucins (s-mucins) were demonstrated histochemically in endoscopic biopsy specimens by using high iron diamine and Alcian blue (pH 1) methods. The prevalence of s-IM, especially the strongly s-positive IM, was significantly higher in GCA patients than in other series or controls of the same age group. Further, s-IM was significantly more common in PA patients and its prevalence higher in GCA relatives and outpatients than in other series or controls. The occurrence of s-IM was also age-dependent and dependent on the extent of IM. It was suggested that the occurrence of s-IM can be used as a sign of lesions that are more closely associated with GCA than IM is in general.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0365-4184
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
217-24
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pubmed:dateRevised |
2009-6-4
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pubmed:meshHeading |
pubmed-meshheading:6160722-Adult,
pubmed-meshheading:6160722-Age Factors,
pubmed-meshheading:6160722-Aged,
pubmed-meshheading:6160722-Alcian Blue,
pubmed-meshheading:6160722-Anemia, Pernicious,
pubmed-meshheading:6160722-Diamines,
pubmed-meshheading:6160722-Female,
pubmed-meshheading:6160722-Gastric Mucosa,
pubmed-meshheading:6160722-Humans,
pubmed-meshheading:6160722-Intestines,
pubmed-meshheading:6160722-Male,
pubmed-meshheading:6160722-Metaplasia,
pubmed-meshheading:6160722-Middle Aged,
pubmed-meshheading:6160722-Mucins,
pubmed-meshheading:6160722-Sex Factors,
pubmed-meshheading:6160722-Staining and Labeling,
pubmed-meshheading:6160722-Stomach Neoplasms
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pubmed:year |
1980
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pubmed:articleTitle |
Intestinal metaplasia with colonic-type sulphomucins in the gastric mucosa; its association with gastric carcinoma.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|