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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1981-1-16
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pubmed:abstractText |
alpha1-macroglobulin (alpha1-M) was demonstrated by indirect immunofluorescence staining on the surface membrane of leucocytes obtained from rat blood and lymphoid tissue. The incidence of alpha1-M positive cells correlated with serum levels of the protein. Compared with blood, a significantly higher percentage of staining cells was demonstrated in spleen and lumbar lymph nodes. During pregnancy, when serum levels of alpha1-M were significantly elevated, the proportion of alpha1-M staining leucocytes increased in blood, Thymus and lymph nodes but the incidence of alpha1-M positive spleen cells was unaffected. The comparatively low incidence of alpha1-M staining thymocytes, together with the presence of alpha1-M on glass-adherent cells and on leucocytes from congenitally athymic rats, suggest that this protein is associated predominantly with B cells and monocytes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0146-7611
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
231-6
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:6159336-Animals,
pubmed-meshheading:6159336-Cell Membrane,
pubmed-meshheading:6159336-Female,
pubmed-meshheading:6159336-Fluorescent Antibody Technique,
pubmed-meshheading:6159336-Leukocytes,
pubmed-meshheading:6159336-Male,
pubmed-meshheading:6159336-Monocytes,
pubmed-meshheading:6159336-Pregnancy,
pubmed-meshheading:6159336-Rats,
pubmed-meshheading:6159336-alpha-Macroglobulins
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pubmed:articleTitle |
Demonstration of serum alpha1-macroglobulin on leucocyte surfaces in non-pregnant and pregnant rats.
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pubmed:publicationType |
Journal Article
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