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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1980-10-27
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pubmed:abstractText |
A competitive radioimmunoassay for immunoconglutinin (IK) was developed using isolated antostimulated rabbit IK labelled with 125I and glutaraldehyde-fixed sheep erythrocytes coated with fixed complement (EAC). IKs in test sera of human or animal origin produced specific inhibition of uptake of [125I]IK onto EAC and this was quantitated by reference to a calibration curve established with pure rabbit IK. Among 20 normal human sera the IK levels were: median 62 microgram/ml, range 41-170 microgram/ml and in 7 rat sera the levels were: median 71 microgram/ml, range 58-80 microgram/ml. Preliminary studies showed raised IK levels in the sera of patients with rheumatoid arthritis and with Crohn's disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0022-1759
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
181-90
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:6156970-Animals,
pubmed-meshheading:6156970-Arthritis, Rheumatoid,
pubmed-meshheading:6156970-Autoantibodies,
pubmed-meshheading:6156970-Binding, Competitive,
pubmed-meshheading:6156970-Complement System Proteins,
pubmed-meshheading:6156970-Crohn Disease,
pubmed-meshheading:6156970-Epitopes,
pubmed-meshheading:6156970-Humans,
pubmed-meshheading:6156970-Rabbits,
pubmed-meshheading:6156970-Radioimmunoassay,
pubmed-meshheading:6156970-Sheep
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pubmed:year |
1980
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pubmed:articleTitle |
Radioimmunoassay for immunoconglutinins.
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pubmed:publicationType |
Journal Article
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