Linked Life Data

6156858

Source:http://linkedlifedata.com/resource/pubmed/id/6156858

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1980-10-27
pubmed:abstractText
In rat the presence of axon collaterals from corticospinal neurons to the contralateral hemisphere has been investigated by means of anatomical and electrophysiological techniques. Anatomical Experiments. Several combinations of fluorescent retrograde tracers were used. In eight rats injections of Evans Blue, "True Blue", "Fast Blue" or DAPI-Primuline were made in areas 10, 6, and 4 and in the most medial part of the S1 granular cortex of one hemisphere, 1.5 mm below cortical surface. These injections were combined with injections of "Fast Blue", DAPI-Primuline, "Granular Blue", "Nuclear Yellow", or Bisbenzimide in the ipsilateral corticospinal tract in the C2 segment. Survival times of the animals varied according to the tracers used. In the non-injected hemisphere the retrogradely labeled corticospinal neurons were present in layer V of especially areas 10, 6, 4 and the medial portion of the S1 granular cortex. However, the retrogradely labeled callosal neurons in these areas were present in all layers except layer I. The labeled callosal and corticospinal neurons in layer V were intermingled and frequently situated very close to one another. However, with none of the tracer combinations were double labeled neurons observed. Electrophysioloogical Experiments. In six rats, layer V neurons of hindlimb-sensorimotor cortex were tested for antidromic responses to stimulation of contralateral corticospinal tract (CST) and corpus callosum (CC). Eighty-five CST neurons were identified, none of which responded antidromically to CC shocks. Eighty-two layer V neurons were identified which responded antidromically to CC shocks, but none of them responded antidromically to CST shocks. CC shocks elicited strong synaptic responses in CST neurons and vice versa. Depth measures indicated extensive intermingling of CST and CC neurons. From both sets of findings it was concluded that, in rat, CST neurons do not give rise to callosal collaterals.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0014-4819
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
433-40
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Absence of callosal collaterals derived from rat corticospinal neurons. A study using fluorescent retrograde tracing and electrophysiological techniques.
pubmed:publicationType
Journal Article