Linked Life Data

6156428

Source:http://linkedlifedata.com/resource/pubmed/id/6156428

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7 Pt 1
pubmed:dateCreated
1980-9-26
pubmed:abstractText
Multiple sclerosis (MS) sera frequently demyelinate organotypic central nervous system (CNS) tissue cultures. To elucidate the possible role of gamma globulins in this form of experimental demyelination we depleted MS sera of all gamma globulins by immunoabsorption and then compared their demyelinating activity with that of the unabsorbed sera. In only 2 out of 16 patients was some demyelinating activity detected in the gamma globulin fraction. In all patients, most of the demyelinating activity was not associated with gamma globulins. In gel filtration experiments, this non-gamma globulin activity was detected in a high-molecular-weight and in a low-molecular-weight fraction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0028-3878
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
749-54
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Multiple sclerosis: serum gamma globulin and demyelination in organ culture.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.