rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
1980-7-28
|
pubmed:abstractText |
A four-drug combination chemotherapy (bleomycin-methotrexate-vinblastine-CCNU) had been used in 38 evaluable patients with recurrent squamous cell carcinoma of the head and neck region on an outpatient basis. A large number of these patients had carcinoma of the oral cavity (45% of total). Nineteen patients (50%) responded to this regimen with a greater than or equal to 50% regression of their measured tumors. The median survival of all patients was 34 weeks. There was one chemotherapy-related death and the overall toxicity was mild. This convenient regimen can be considered a useful alternative to more aggressive therapy.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0008-543X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
45
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2038-41
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6154522-Aged,
pubmed-meshheading:6154522-Antineoplastic Agents,
pubmed-meshheading:6154522-Bleomycin,
pubmed-meshheading:6154522-Carcinoma, Squamous Cell,
pubmed-meshheading:6154522-Clinical Trials as Topic,
pubmed-meshheading:6154522-Drug Administration Schedule,
pubmed-meshheading:6154522-Female,
pubmed-meshheading:6154522-Head and Neck Neoplasms,
pubmed-meshheading:6154522-Humans,
pubmed-meshheading:6154522-Lomustine,
pubmed-meshheading:6154522-Male,
pubmed-meshheading:6154522-Methotrexate,
pubmed-meshheading:6154522-Middle Aged,
pubmed-meshheading:6154522-Neoplasm Recurrence, Local,
pubmed-meshheading:6154522-Time Factors,
pubmed-meshheading:6154522-Vinblastine
|
pubmed:year |
1980
|
pubmed:articleTitle |
A trial of outpatient chemotherapy for recurrent head and neck tumors.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.
|