Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1985-4-19
pubmed:abstractText
Somatostatin- and vasoactive intestinal polypeptide (VIP)-like immunoreactivities (SLI and VLI, respectively) were measured, by radioimmunoassay, in 21 regions of postmortem brains from 7 histologically verified cases of patients with Alzheimer-type dementia (ATD) and 10 histologically normal controls. SLI was significantly reduced in the orbital cortex, hippocampus and putamen of ATD brains. Significant reduction of VLI in the ATD brains was also found in the insular and angulate cortex, which have not previously been examined biochemically for peptides. These results suggest that involvement of not only somotostatin- but also VIP-containing neurons may not be ruled out in ATD brains.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
23
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
73-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Somatostatin and vasoactive intestinal polypeptide in postmortem brains from patients with Alzheimer-type dementia.
pubmed:publicationType
Journal Article