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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1985-3-5
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pubmed:abstractText |
The Beta-Blocker Heart Attack Trial (BHAT) was a multicentered, double-blind, randomized, placebo-controlled clinical trial designed to test the efficacy of long-term therapy with propranolol given to survivors of an acute myocardial infarction (MI). Three thousand, eight hundred and thirty-seven men and women, aged 30-69 years, were randomized into either the propranolol or placebo group 5 to 21 days after hospital admission for the MI and were followed at quarterly visits for 12 to 40 months (mean = 25 months). The primary outcome for the trial was all-cause mortality. This article describes the design and baseline findings of the trial. Included is a description of the historical background for the trial and the procedures employed in patient recruitment, randomization, treatment and follow-up. Also included is a comparison between the BHAT population and post-myocardial infarction patients enrolled in the other long-term trials of beta-blockers.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0197-2456
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
5
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
382-437
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6151483-Adrenergic beta-Antagonists,
pubmed-meshheading:6151483-Clinical Trials as Topic,
pubmed-meshheading:6151483-Double-Blind Method,
pubmed-meshheading:6151483-Follow-Up Studies,
pubmed-meshheading:6151483-Humans,
pubmed-meshheading:6151483-Myocardial Infarction,
pubmed-meshheading:6151483-Placebos,
pubmed-meshheading:6151483-Propranolol,
pubmed-meshheading:6151483-Random Allocation,
pubmed-meshheading:6151483-Recurrence
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pubmed:year |
1984
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pubmed:articleTitle |
Beta-blocker heart attack trial: design, methods, and baseline results. Beta-blocker heart attack trial research group.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial
|