Linked Life Data

6150907

Source:http://linkedlifedata.com/resource/pubmed/id/6150907

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1985-2-5
pubmed:abstractText
Animal cells have specific pathways to transport macromolecules from their surrounding environment to their interior, and from internal compartments to the cell surface or other intracellular locations. Many of these movements appear to be receptor-dependent processes in which specific membrane receptors bind macromolecules, segregate them into discrete membrane-limited compartments, and move the molecules to new locations. Such processes include the clustering and internalization of receptor-bound ligands at the cell surface in clathrin-coated pits, the formation of endocytic vesicles (receptosomes) from coated pits, the movement of receptosomes by saltatory motion to the Golgi system, the concentration of materials in the coated pits of the Golgi system that are destined for delivery to lysosomes, and the directed traffic of materials destined for exocytosis out of the Golgi to the cell surface. This review describes some of the experiments which have led to our current understanding of the various organelles involved in this traffic and some of the biochemical mechanisms involved.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0074-7696
pubmed:author
pubmed:issnType
Print
pubmed:volume
92
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
51-92
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Endocytosis and exocytosis: current concepts of vesicle traffic in animal cells.
pubmed:publicationType
Journal Article, Review