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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
1985-2-15
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pubmed:abstractText |
Plasma concentrations of gonadotropin, prolactin and hypothalamic tyrosine hydroxylase (TH) activity were measured in ovariectomized rats treated with aminooxyacetic acid (AOAA), a drug which elevates brain GABA levels. Hypothalamic TH activity was significantly increased with a significant decrease in prolactin (Prl) release. Plasma levels of gonadotropins were not modified by AOAA. These results support an inhibitory action of GABA on Prl release possibly mediated through hypothalamic dopamine.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0014-4754
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1422-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6150866-Acetic Acids,
pubmed-meshheading:6150866-Aminooxyacetic Acid,
pubmed-meshheading:6150866-Animals,
pubmed-meshheading:6150866-Castration,
pubmed-meshheading:6150866-Female,
pubmed-meshheading:6150866-Follicle Stimulating Hormone,
pubmed-meshheading:6150866-Gonadotropins, Pituitary,
pubmed-meshheading:6150866-Hypothalamus,
pubmed-meshheading:6150866-Luteinizing Hormone,
pubmed-meshheading:6150866-Prolactin,
pubmed-meshheading:6150866-Rats,
pubmed-meshheading:6150866-Rats, Inbred Strains,
pubmed-meshheading:6150866-Tyrosine 3-Monooxygenase,
pubmed-meshheading:6150866-gamma-Aminobutyric Acid
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pubmed:year |
1984
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pubmed:articleTitle |
Hypothalamic tyrosine hydroxylase activity, plasma gonadotropin and prolactin levels after aminooxyacetic acid in ovariectomized rats.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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