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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1984-12-28
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pubmed:abstractText |
A new method has been developed to raise monoclonal anti-idiotypic antibodies. Monoclonal anti-idiotypic antibodies were obtained by fusion of NS-1 myeloma cells with splenocytes of mice immunised by intravenous injections of fixed hybridoma cells bearing a monoclonal antibody specific for beta-adrenergic ligands. New screening tests were developed to analyse the resulting hybridoma supernatants for different anti-idiotypic properties. Among 23 hybridoma supernatants recognising the idiotype, 6 were found to inhibit hapten binding and 3 of these recognised beta-adrenergic receptors.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-1759
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
16
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pubmed:volume |
74
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
163-71
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6150059-Adrenergic beta-Antagonists,
pubmed-meshheading:6150059-Animals,
pubmed-meshheading:6150059-Antibodies, Monoclonal,
pubmed-meshheading:6150059-Carcinoma, Squamous Cell,
pubmed-meshheading:6150059-Cell Line,
pubmed-meshheading:6150059-Humans,
pubmed-meshheading:6150059-Hybridomas,
pubmed-meshheading:6150059-Immunoglobulin Idiotypes,
pubmed-meshheading:6150059-Ligands,
pubmed-meshheading:6150059-Lymphocytes,
pubmed-meshheading:6150059-Mice,
pubmed-meshheading:6150059-Mice, Inbred BALB C,
pubmed-meshheading:6150059-Plasmacytoma,
pubmed-meshheading:6150059-Receptors, Adrenergic, beta
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pubmed:year |
1984
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pubmed:articleTitle |
Production and detection of monoclonal anti-idiotype antibodies directed against a monoclonal anti-beta-adrenergic ligand antibody.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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