| pubmed-article:6149809 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6149809 | lifeskim:mentions | umls-concept:C0001645 | lld:lifeskim |
| pubmed-article:6149809 | lifeskim:mentions | umls-concept:C0441472 | lld:lifeskim |
| pubmed-article:6149809 | lifeskim:mentions | umls-concept:C0456387 | lld:lifeskim |
| pubmed-article:6149809 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:6149809 | pubmed:dateCreated | 1985-1-17 | lld:pubmed |
| pubmed-article:6149809 | pubmed:abstractText | We have studied the effect of the intravenous administration of the following drugs on ventricular refractoriness in 35 experiments in open chested beagle dogs: atenolol 0.2 mg X kg-1; nadolol 0.05 mg X kg-1; oxprenolol 0.2 mg X kg-1; pindolol 0.04 mg X kg-1; propranolol 0.2 mg X kg-1; sotalol 0.6 mg X kg-1 and timolol 0.1 mg X kg-1. The animals were anaesthetised with chloralose and urethane. Measurements were made of left ventricular epicardial monophasic action potentials (MAP) (n = 35) and the left ventricular paced evoked response (PER) (n = 25) at a fixed paced cycle length of between 220 and 310 ms. The animals were initially beta-blocked with iv pindolol or propranolol and the drug under study then administered iv 10 min later. The results were as follows: (control and post drug administration) MAP: nadolol 151 +/- 12 SD to 172 +/- 13 SD (p less than 0.001); oxprenolol 153 +/- 21 to 178 +/- 20 (p less than 0.001); sotalol 153 +/- 19 to 176 +/- 20 (p less than 0.001); atenolol 152 +/- 25 to 153 +/- 23 (NS); pindolol 149 +/- 11 to 152 +/- 10 (NS); propranolol 152 +/- 26 to 155 +/- 26 (NS); timolol 144 +/- 23 to 144 +/- 21 (NS). PER: nadolol 172 +/- 14 to 190 +/- 20 (p less than 0.001); oxprenolol 164 +/- 16 to 188 +/- 15 (p less than 0.001); propranolol 166 +/- 22 to 173 +/- 18 (NS).(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:6149809 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6149809 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6149809 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6149809 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6149809 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6149809 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6149809 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6149809 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6149809 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6149809 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6149809 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6149809 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6149809 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6149809 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:6149809 | pubmed:issn | 0008-6363 | lld:pubmed |
| pubmed-article:6149809 | pubmed:author | pubmed-author:TaggartPP | lld:pubmed |
| pubmed-article:6149809 | pubmed:author | pubmed-author:DonaldsonRR | lld:pubmed |
| pubmed-article:6149809 | pubmed:author | pubmed-author:AbelBB | lld:pubmed |
| pubmed-article:6149809 | pubmed:author | pubmed-author:NashatFF | lld:pubmed |
| pubmed-article:6149809 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6149809 | pubmed:volume | 18 | lld:pubmed |
| pubmed-article:6149809 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6149809 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6149809 | pubmed:pagination | 683-9 | lld:pubmed |
| pubmed-article:6149809 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:meshHeading | pubmed-meshheading:6149809-... | lld:pubmed |
| pubmed-article:6149809 | pubmed:year | 1984 | lld:pubmed |
| pubmed-article:6149809 | pubmed:articleTitle | Class III action of beta-blocking agents. | lld:pubmed |
| pubmed-article:6149809 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6149809 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6149809 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6149809 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6149809 | lld:pubmed |
