Linked Life Data

6149068

Source:http://linkedlifedata.com/resource/pubmed/id/6149068

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-11-28
pubmed:abstractText
The effects of acetylcholine (ACh), carbamylcholine and gamma-aminobutyric acid (GABA) on the spike activity of uropod motoneurons were investigated electrophysiologically in the crayfish Procambarus clarkii Girard and Cambaroides japonicus de Haan. High concentrations of ACh were required to bring about an increase in the spike discharge of uropod motoneurons while carbamylcholine, which is not destroyed by cholinesterase, caused a marked increase in the motoneuron spike discharge even in low concentrations. Application of GABA in concentrations of 10(-5)-10(-2) M caused the decrease in the spike discharge of uropod motoneurons. Under the condition that the synaptic transmission onto uropod motoneurons was blocked by perfusing EGTA containing Ca2+-free saline with high-Mg2+, ACh increased the spike discharge of uropod motoneurons whereas GABA decreased it. The results suggested that ACh and GABA function as excitatory and inhibitory transmitters, respectively, in the crayfish central nervous system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0742-8413
pubmed:author
pubmed:issnType
Print
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
295-300
pubmed:dateRevised
2007-7-23
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
The effects of acetylcholine, carbamylcholine and gamma-aminobutyric acid on uropod motoneurons in the crayfish Procambarus clarkii and Cambaroides japonicus.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't