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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8401
|
pubmed:dateCreated |
1984-10-3
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pubmed:abstractText |
22 cirrhotic patients with chronic encephalopathy were given oral zinc supplementation or placebo in a double-blind randomised trial. In the group which received zinc acetate 600 mg a day for 7 days, serum zinc had been restored to normal by day 8. On day 8 hepatic encephalopathy, as assessed by a trailmaking test, was improved in the supplemented group but not in the placebo group. There was also a significant increase in blood urea nitrogen in the supplemented group. Short-term oral zinc supplementation probably improved hepatic encephalopathy by correcting the zinc deficiency that compromises conversion of ammonia to urea. The duration of this improvement requires further investigation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
2
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
493-5
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6147551-Acetic Acid,
pubmed-meshheading:6147551-Acetic Acids,
pubmed-meshheading:6147551-Administration, Oral,
pubmed-meshheading:6147551-Blood Urea Nitrogen,
pubmed-meshheading:6147551-Chronic Disease,
pubmed-meshheading:6147551-Clinical Trials as Topic,
pubmed-meshheading:6147551-Copper,
pubmed-meshheading:6147551-Double-Blind Method,
pubmed-meshheading:6147551-Female,
pubmed-meshheading:6147551-Hepatic Encephalopathy,
pubmed-meshheading:6147551-Humans,
pubmed-meshheading:6147551-Male,
pubmed-meshheading:6147551-Prospective Studies,
pubmed-meshheading:6147551-Random Allocation,
pubmed-meshheading:6147551-Trail Making Test,
pubmed-meshheading:6147551-Zinc
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pubmed:year |
1984
|
pubmed:articleTitle |
Oral zinc supplementation improves hepatic encephalopathy. Results of a randomised controlled trial.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|