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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8400
|
pubmed:dateCreated |
1984-9-25
|
pubmed:abstractText |
62 severely anaemic Gambian children who were transfused with whole blood not screened for hepatitis B surface antigen (HBsAg) were followed for evidence of hepatitis B virus (HBV) infection over six months. 89% of donors and 44% of recipients before their transfusion had at least one HBV marker. Of the 54 recipient children surviving for the follow-up period, only 1 had a transient rise in liver enzymes. In 13 (37%) of 35 previously uninfected children HBV infection developed within twelve weeks of transfusion. Only 1 of these 13 children followed up at one year had become a persistent HBsAg carrier. The rate at which this cohort acquired persistent HBV infection or clinically important hepatitis was no greater than that in a cohort of similarly aged, nontransfused, children not admitted to hospital. In sub-Saharan Black Africa, where 15% of children have persistent HBV infection by the age of 10 years, HBV screening programmes in transfusion centres cannot at present be justified.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
25
|
pubmed:volume |
2
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
449-52
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6147513-Blood Transfusion,
pubmed-meshheading:6147513-Child,
pubmed-meshheading:6147513-Child, Preschool,
pubmed-meshheading:6147513-Female,
pubmed-meshheading:6147513-Gambia,
pubmed-meshheading:6147513-Hepatitis B,
pubmed-meshheading:6147513-Hepatitis B Antibodies,
pubmed-meshheading:6147513-Hepatitis B Core Antigens,
pubmed-meshheading:6147513-Hepatitis B Surface Antigens,
pubmed-meshheading:6147513-Humans,
pubmed-meshheading:6147513-Infant,
pubmed-meshheading:6147513-Male
|
pubmed:year |
1984
|
pubmed:articleTitle |
Screening for hepatitis B virus markers is not justified in West African transfusion centres.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|