Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1984-9-19
|
| pubmed:abstractText |
We have found that rat hepatoma cells (R-Y121B) retain alkaline phosphatase activity, and that this enzyme activity is increased by cycloheximide. Actinomycin D also increased the enzyme activity. This increase due to actinomycin D was partially inhibited by cycloheximide. The characteristics of alkaline phosphatase of the cells treated or untreated with cycloheximide or actinomycin D were similar to each other; they were heat labile and the enzyme reaction was strongly inhibited by L-homoarginine, but weakly by L-phenylalanine. The increase in alkaline phosphatase activity with cycloheximide has been termed a 'superactivation' of alkaline phosphatase.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0022-3573
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
36
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
473-5
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:6146696-Alkaline Phosphatase,
pubmed-meshheading:6146696-Animals,
pubmed-meshheading:6146696-Cells, Cultured,
pubmed-meshheading:6146696-Cycloheximide,
pubmed-meshheading:6146696-Dactinomycin,
pubmed-meshheading:6146696-Enzyme Activation,
pubmed-meshheading:6146696-Liver Neoplasms, Experimental,
pubmed-meshheading:6146696-Rats
|
| pubmed:year |
1984
|
| pubmed:articleTitle |
'Superactivation' of alkaline phosphatase activity by cycloheximide in rat hepatoma cell cultures.
|
| pubmed:publicationType |
Journal Article
|