Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-8-7
pubmed:abstractText
Somatostatin (SRIF), the somatotropin release inhibiting factor of the hypothalamus, has been reported to inhibit the production of angiotensin II (AII)-stimulated aldosterone in the rat adrenal glomerulosa cells. Since the interrenal of the frog is the homolog of mammalian adrenal zona glomerulosa, the effect of synthetic SRIF on perifused dice of Rana ridibunda was tested. Graded doses of SRIF did not modify the spontaneous production of corticosterone and aldosterone. The highest concentration of SRIF (10(-5) M) did not alter the stimulatory effect of the AII agonist [Sar1-Val5] AII upon corticosteroidogenesis. Thus, in apparent contradiction to recent findings in mammals, SRIF did not alter the effect of AII in the frog interrenal cell.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0016-6480
pubmed:author
pubmed:issnType
Print
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
333-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
In vitro study of frog (Rana ridibunda Pallas) interrenal function by use of a simplified perifusion system. VII. Lack of effect of somatostatin on angiotensin-induced corticosteroid production.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't