Linked Life Data

6145505

Source:http://linkedlifedata.com/resource/pubmed/id/6145505

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-8-17
pubmed:abstractText
Mouse spinal cord neurons grown in tissue culture were impaled with a pair of microelectrodes containing 1 M CsCl and voltage-clamped. Membrane currents evoked by excitatory amino acids were studied over the potential range -70 to +20 mV. Glutamate currents behaved as though generated by simultaneous activation of two conductance mechanisms, one voltage-sensitive, the other conventional. Block of NMDA receptors with the competitive antagonist 2-APV removed the voltage-sensitive component of the glutamate response. These results help to explain the paradoxical lack of conductance-change previously reported for glutamate responses recorded in the mammalian CNS.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
3
pubmed:volume
301
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
375-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Glutamate currents in mammalian spinal neurons: resolution of a paradox.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't