Linked Life Data

6144358

Source:http://linkedlifedata.com/resource/pubmed/id/6144358

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-7-18
pubmed:abstractText
The in vivo rate of 3,4-dihydroxyphenylalanine (DOPA) accumulation was measured in light-adapted retinas of normal and diabetic albino rats. DOPA accumulation was significantly below normal in diabetic retinas; tyrosine levels were also reduced. In vitro tyrosine hydroxylase activity was normal. The administration of tyrosine methylester (500 mg/kg i.p.) to diabetic animals significantly raised retinal tyrosine levels and enhanced DOPA accumulation. Reduced tyrosine levels may therefore contribute to the observed reduction in in vivo tyrosine hydroxylation rate in the diabetic retina.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
23
pubmed:volume
298
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
167-70
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
In vivo tyrosine hydroxylation in the diabetic rat retina: effect of tyrosine administration.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.