Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1984-5-10
|
pubmed:abstractText |
Different, dose-dependent effects of verapamil inhalation on histamine-induced bronchoconstriction in anaesthetized dogs are reported. Cumulative histamine dose-response curves were obtained on three groups each consisting of six dogs. These groups were: A - after atropine sulphate (1 mg/kg); B - after atropine sulphate and verapamil (approximately 0.5 mg/kg); C - after atropine sulphate and verapamil (approximately 5.0 mg/kg). Total lung resistance (R1) was measured as the indicator of bronchoconstriction. The mean maximal response of R1 in B was significant greater (p less than 0.01) than in A and C, while no significant difference was observed between A and C. A possible mechanism is postulated.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0301-4533
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
267
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
328-34
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6143539-Aerosols,
pubmed-meshheading:6143539-Airway Resistance,
pubmed-meshheading:6143539-Anesthesia,
pubmed-meshheading:6143539-Animals,
pubmed-meshheading:6143539-Atropine,
pubmed-meshheading:6143539-Bronchi,
pubmed-meshheading:6143539-Dogs,
pubmed-meshheading:6143539-Dose-Response Relationship, Drug,
pubmed-meshheading:6143539-Female,
pubmed-meshheading:6143539-Histamine H1 Antagonists,
pubmed-meshheading:6143539-Male,
pubmed-meshheading:6143539-Verapamil
|
pubmed:year |
1984
|
pubmed:articleTitle |
Different, dose-dependent effects of verapamil inhalation on histamine-induced bronchoconstriction in anaesthetized dogs.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|