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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8371
|
| pubmed:dateCreated |
1984-5-4
|
| pubmed:abstractText |
Two infants presented with biopsy-proven histiocytosis X affecting multiple sites. Since neither showed evidence of organ failure or of constitutional upset, no specific therapy was given. In each case there was long-lasting spontaneous regression of disease. Analysis of blood mononuclear cells revealed a raised T4:T8 (helper:suppressor T lymphocyte) ratio at diagnosis but a normal ratio during remission. These observations support the argument that multi-system histiocytosis X, even in infants (Letterer-Siwe disease), is not a malignancy and that an "expectant" treatment policy may be indicated in selected patients.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0140-6736
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
4
|
| pubmed:volume |
1
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
253-4
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6142997-Biopsy,
pubmed-meshheading:6142997-Female,
pubmed-meshheading:6142997-Histiocytosis, Langerhans-Cell,
pubmed-meshheading:6142997-Humans,
pubmed-meshheading:6142997-Infant,
pubmed-meshheading:6142997-Infant, Newborn,
pubmed-meshheading:6142997-Lung,
pubmed-meshheading:6142997-Lung Compliance,
pubmed-meshheading:6142997-Male,
pubmed-meshheading:6142997-Skin,
pubmed-meshheading:6142997-Skin Diseases,
pubmed-meshheading:6142997-T-Lymphocytes, Helper-Inducer,
pubmed-meshheading:6142997-T-Lymphocytes, Regulatory
|
| pubmed:year |
1984
|
| pubmed:articleTitle |
Spontaneous remission of multi-system histiocytosis X.
|
| pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|