Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1984-5-24
pubmed:abstractText
The concept of peripheral presynaptic regulation of neuronal norepinephrine (NE) release via alpha 2 adrenoreceptors has received extensive support from in vitro evidence. Despite this, the importance of such a system under physiological and pathophysiological conditions remains to be defined in humans. This largely reflects the limitations of using plasma NE as an index of neuronal amine release in vivo and the difficulties of interpreting the hemodynamic responses to adrenoreceptor agonists or antagonists administered in vivo. Efficient probes and sensitive indices of neuronal NE release are required to clarify the importance of peripheral presynaptic mechanisms in humans.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0014-9446
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1379-81
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Peripheral presynaptic adrenoreceptor regulation of norepinephrine release in humans.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.