Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12A
pubmed:dateCreated
1984-3-14
pubmed:abstractText
Acute administration of excitatory amino acids alters the release of anterior pituitary hormones. The neurochemical effects of monosodium glutamate (MSG) administration to adult mice were examined 30 minutes and 60 days after an acute injection (4 mg/g). The permanent effects of an acute injection of MSG were limited to a slight loss of neurons in the ventral arcuate nucleus and a 21% reduction in hypothalamic 5-HIAA levels. Thirty minutes after MSG administration hypothalamic DA and DOPAC levels were increased 27% and 25%, respectively and MOPEG levels were increased 75% in the hypothalamus and 34% in the remaining whole brain. These findings show that the acute administration of MSG results in alterations in hypothalamic monoamine metabolism which may be related to the neuroendocrine consequences of excitatory amino acid administration.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0028-3908
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1417-9
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Acute and long lasting neurochemical effects of monosodium glutamate administration to mice.
pubmed:publicationType
Journal Article