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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1984-2-24
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pubmed:abstractText |
Female Sprague-Dawley rats were fed polybrominated biphenyls (PBBs) for 15 or 140 days after a 70% partial hepatectomy and diethylnitrosamine administration (10 mg/kg body weight) to determine the effect of varying the length of exposure to PBBs on the enhancement of gamma-glutamyl transpeptidase enzyme-altered foci. fireMaster BP-6R, a commercial mixture of PBBs, was fed to rats at a dietary concentration of 100 mg/kg for 15 days or 10 mg/kg for 140 days during the promotion phase of a two-stage hepatocarcinogenesis assay. Results indicate that short term exposure to PBBs is as effective as long term exposure in enhancing the development of enzyme-altered foci.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0143-3334
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
63-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6140088-Adipose Tissue,
pubmed-meshheading:6140088-Animals,
pubmed-meshheading:6140088-Body Weight,
pubmed-meshheading:6140088-Dose-Response Relationship, Drug,
pubmed-meshheading:6140088-Female,
pubmed-meshheading:6140088-Liver,
pubmed-meshheading:6140088-Liver Neoplasms, Experimental,
pubmed-meshheading:6140088-Microsomes, Liver,
pubmed-meshheading:6140088-Polybrominated Biphenyls,
pubmed-meshheading:6140088-Rats,
pubmed-meshheading:6140088-gamma-Glutamyltransferase
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pubmed:year |
1984
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pubmed:articleTitle |
Effect of varying the length of exposure to polybrominated biphenyls on the development of gamma-glutamyl transpeptidase enzyme-altered foci.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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