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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1984-1-26
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pubmed:abstractText |
Fifty unilaterally cryptorchid boys aged 3 to 8 years were randomly and blindly allocated to treatment with luteinizing hormone releasing hormone or placebo intranasally. In the treated group, no significant descent of the undescended testis was found, whereas a minor downward movement of the scrotal testis occurred (P less than 0.001), probably as a result of decreased retraction by the cremaster muscle. Basal serum testosterone concentrations and testicular volume increased after treatment (P less than 0.01 and P less than 0.001, respectively). The response to an acute LHRH test, 100 micrograms/m2 body surface IV, before and after treatment, showed an increase in the luteinizing hormone peak value and a decrease in the follicle-stimulating hormone response in a significant number of patients (P less than 0.001). In the individual patient, there was a positive correlation between the increase in basal serum testosterone concentration and the degree of downward movement of the undescended testis (P less than 0.05).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0022-3476
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
892-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6139422-Child,
pubmed-meshheading:6139422-Child, Preschool,
pubmed-meshheading:6139422-Cryptorchidism,
pubmed-meshheading:6139422-Double-Blind Method,
pubmed-meshheading:6139422-Follicle Stimulating Hormone,
pubmed-meshheading:6139422-Gonadotropin-Releasing Hormone,
pubmed-meshheading:6139422-Humans,
pubmed-meshheading:6139422-Luteinizing Hormone,
pubmed-meshheading:6139422-Male,
pubmed-meshheading:6139422-Random Allocation,
pubmed-meshheading:6139422-Testis,
pubmed-meshheading:6139422-Testosterone
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pubmed:year |
1983
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pubmed:articleTitle |
LHRH treatment in unilateral cryptorchidism: effect on testicular descent and hormonal response.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|