Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11 Pt 2
pubmed:dateCreated
1984-1-7
pubmed:abstractText
The available data from animal and human studies on mechanisms postulated to be involved in the production and mediation of anxiety are reviewed. Effects of specific agents used to treat clinical anxiety, and/or studied in research on experimentally induced behaviors resembling clinical anxiety, are examined in terms of their implications for the etiology and management of these symptoms. In the search for an ideal anxiolytic (i.e., one which would selectively decrease anxiety without producing sedation, cognitive or psychomotor impairment, tolerance/dependence, untoward psychologic reactions, interactions with CNS depressants, or morbidity risk in overdose), recent research has focused on several nonbenzodiazepine substances. Results of these studies indicate that continued study and development of nonbenzodiazepine anxiolytics will facilitate achievement of optimum pharmacotherapeutic approaches to the management of clinical anxiety.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0160-6689
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
45-57
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Anxiolytic profiles.
pubmed:publicationType
Journal Article, Review