Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8359
pubmed:dateCreated
1983-12-17
pubmed:abstractText
Transplacental transmission of hepatitis B virus infection was studied in 51 Senegalese neonates born to mothers who were chronic carriers of HBsAg. 13 mothers were positive for both HBsAg and HBeAg. Mother-to-infant transmission of these two markers was different with 3 children being HBsAg positive and HBeAg negative at birth and 6 being HBsAg negative but HBeAg positive. At birth none of the 51 children had anti-HBc IgM detected by a highly specific enzyme immunoassay, indicating that none had had a primary immune response in utero to HBV infection. These HBV serum markers in newborn infants indicate contamination by maternal blood at delivery rather than active infection in utero. Prophylaxis at birth is advisable in children of mothers who are chronic carriers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0140-6736
pubmed:author
pubmed:issnType
Print
pubmed:day
12
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1103-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Lack of anti-HBc IgM in neonates with HBsAg carrier mothers argues against transplacental transmission of hepatitis B virus infection.
pubmed:publicationType
Journal Article