Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-9-23
pubmed:abstractText
Microfilariae of Dirofilaria immitis were recovered from an experimentally infected dog and inoculated intravenously into adult female BALB/c mice. Each mouse received 1 X 10(5) microfilariae. In one experiment mice were sublethally irradiated with gamma radiation 24 h prior to microfilarial inoculation; microfilariae were counted at 11.00 and 23.00 h 7, 14, 21, 28, 35 and 42 days after inoculation. A similar experiment was performed in nonirradiated mice to ensure that sublethal irradiation had not caused microfilarial periodicity. In a third experiment microfilaria numbers were determined in sublethally irradiated mice at 4-h intervals for 48 h beginning 14 days after microfilarial inoculation; microfilaria numbers at each bleeding were compared to microfilarial density at the same time in the donor dog. In a fourth experiment 2 groups of mice were irradiated, inoculated and bled as before; one group was acclimated to light from 07.00 h to 19.00 h, whereas the other group was acclimated to light from 19.00 h to 07.00 h. The microfilaremia was subperiodic, varying regularly with time in both the dog and mice. Microfilariae in the dog reached maximum numbers during light hours. In each experiment, regardless of actual time, microfilariae in mice reached maximum numbers during dark hours.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0001-706X
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
121-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Periodicity of Dirofilaria immitis microfilariae in canine and murine hosts.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.