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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1983-8-26
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pubmed:abstractText |
Precursors of cytotoxic lymphoid cells obtained from mice treated with cyclophosphamide (CY) can be expanded in culture by alloantigens in the presence of purified human interleukin 2 (IL 2). Similarly, IL 2 delivered in vivo in a rate-controlled manner enhances cytotoxic activity in mice that are immunosuppressed by high doses of CY. The effector cells are Thy-1.2+ and are not elicited in the absence of antigen.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-1767
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
131
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
806-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6134774-Animals,
pubmed-meshheading:6134774-Antigens, Surface,
pubmed-meshheading:6134774-Antigens, Thy-1,
pubmed-meshheading:6134774-Cyclophosphamide,
pubmed-meshheading:6134774-Drug Resistance,
pubmed-meshheading:6134774-Interleukin-2,
pubmed-meshheading:6134774-Isoantigens,
pubmed-meshheading:6134774-Male,
pubmed-meshheading:6134774-Mice,
pubmed-meshheading:6134774-Mice, Inbred C57BL,
pubmed-meshheading:6134774-Mice, Inbred DBA,
pubmed-meshheading:6134774-T-Lymphocytes, Cytotoxic
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pubmed:year |
1983
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pubmed:articleTitle |
Expansion of cyclophosphamide-resistant cytotoxic precursors in vitro and in vivo by purified human interleukin 2.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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