Linked Life Data

6134729

Source:http://linkedlifedata.com/resource/pubmed/id/6134729

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
1983-8-17
pubmed:abstractText
C-proteins have been isolated from rabbit red skeletal muscle (soleus and semitendinosus) and cardiac muscle and their structure and properties compared with those of white muscle C-protein. The Mr of white, red, and cardiac C-proteins are 135,000, 145,000, and 150,000, respectively, and their s20,w values are 4.3, 3.8, and 4.8 S, indicating that red C-protein is more asymmetric than the other two. They elute quite differently from hydroxylapatite columns. Two-dimensional CNBr peptide maps show extensive differences in primary structure, and anti-white C-protein does not precipitate red or cardiac C-protein. Despite these structural differences, all three C-proteins bind equally to white, red, or cardiac myosin and to actin. All three have the same effects on actomyosin ATPase in 50 mM KCl; they inhibit red and white skeletal actomyosins but slightly activate cardiac actomyosin. X-protein, a 140,000-dalton contaminant of white C-protein, was also investigated. It is very similar to red C-protein in elution from hydroxylapatite columns, S20,w, amino acid composition, and primary structure, but small differences in Mr and peptide maps indicate that the two proteins are probably not identical.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0021-9258
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
258
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
8395-401
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
The C-proteins of rabbit red, white, and cardiac muscles.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't