Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-5-5
pubmed:abstractText
Since NZB mice manifest evidence of intense B cell activation, the state of activation of their T cells was explored. Electron microscopic examination and automated laser light scatter analysis demonstrated the presence of many blast lymphocytes in the spleens of aging NZB mice but not in controls. Only 45% of these large cells were B cells by the criterion of stainable surface IgM. NZB T and B cells were separated using the fluorescence-activated cell sorter; cytographic analysis revealed that both T and B cell populations contained substantial numbers of blast cells. The data thus indicated that T cells, as well as B cells, undergo activation as autoimmunity develops in NZB mice.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0141-2760
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
199-205
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Activation of T and B lymphocytes in NZB mice.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.