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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1983-4-21
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pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/ANESTHESIA,
http://linkedlifedata.com/resource/pubmed/keyword/Biology,
http://linkedlifedata.com/resource/pubmed/keyword/Cardiovascular Effects,
http://linkedlifedata.com/resource/pubmed/keyword/Contraception,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Agents,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Agents, Female,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive...,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Methods--side effects,
http://linkedlifedata.com/resource/pubmed/keyword/DRUGS,
http://linkedlifedata.com/resource/pubmed/keyword/Diseases,
http://linkedlifedata.com/resource/pubmed/keyword/Family Planning,
http://linkedlifedata.com/resource/pubmed/keyword/HEART DISEASES,
http://linkedlifedata.com/resource/pubmed/keyword/Oral...,
http://linkedlifedata.com/resource/pubmed/keyword/Oral Contraceptives--side effects,
http://linkedlifedata.com/resource/pubmed/keyword/Physiology,
http://linkedlifedata.com/resource/pubmed/keyword/Reproductive Control Agents,
http://linkedlifedata.com/resource/pubmed/keyword/Treatment
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pubmed:language |
fre
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0032-5821
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
347-53
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pubmed:dateRevised |
2006-11-15
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pubmed:otherAbstract |
PIP: Cardiac accidents induced by various types of drugs are examined and risk factors are identified in this article. Digitalis preparations are responsible for the largest number of accidents, but their frequency diminishes when prescription rules are respected. Overdoses are often announced by digestive complaints, while more serious problems arise at the stage of intoxication. Theophylline is used as a bronchial muscle relaxant but also has a cardiac effect. All antiarhythmics except bretylate are negative inotropes and can aggravate cardiac insufficiency. Beta-blockers were relatively well tolerated if the contraindications are respected. The main risks are decompensation for a cardiac insufficiency and aggravation of an auriculoventricular block. The risks of antiangina preparations are mostly provoked by their vasodilation action. Neurotropic drugs usually entail minimal alterations in the electrocardiogram but a variety of serious problems may arise with massive ingestion. Cardiotoxicity is rare in anticancer drugs and has mostly been noted in anthracyclinic products. Accidents with local anesthetics are not rare despite their daily use, while general anesthetics vary in their risk levels. A variety of other medications have been found or suspected to entail risks. Myocardial infarction in young, healthy oral contraceptive (OC) users has been observed but the mechanism of action is unclear. The necessity of ruling out risk factors before prescribing combined pills has been underlined. It is difficult to compile a complete list of all drugs having cardiovascular repercussions and the action of some drugs is probably still undiscovered. In most cases the complications are dose-related and predictable. Exceptions to this rule exist, as with OCs.
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pubmed:meshHeading |
pubmed-meshheading:6131412-Adrenergic beta-Antagonists,
pubmed-meshheading:6131412-Anesthetics,
pubmed-meshheading:6131412-Angina Pectoris,
pubmed-meshheading:6131412-Animals,
pubmed-meshheading:6131412-Anti-Arrhythmia Agents,
pubmed-meshheading:6131412-Antineoplastic Agents,
pubmed-meshheading:6131412-Antipsychotic Agents,
pubmed-meshheading:6131412-Cardiovascular System,
pubmed-meshheading:6131412-Contraceptives, Oral,
pubmed-meshheading:6131412-Digitalis Glycosides,
pubmed-meshheading:6131412-Drug Hypersensitivity,
pubmed-meshheading:6131412-Drug Therapy,
pubmed-meshheading:6131412-Female,
pubmed-meshheading:6131412-Heart,
pubmed-meshheading:6131412-Heart Block,
pubmed-meshheading:6131412-Humans,
pubmed-meshheading:6131412-Myocardial Infarction,
pubmed-meshheading:6131412-Phenothiazines,
pubmed-meshheading:6131412-Theophylline
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pubmed:year |
1982
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pubmed:articleTitle |
[Drugs and the cardiovascular system].
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pubmed:publicationType |
Journal Article,
English Abstract
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