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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
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pubmed:dateCreated |
1983-3-11
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pubmed:abstractText |
Mesenchymal cells from the prefusion human embryonic palate have been established in culture and can be grown in either a serum-free hormone-supplemented medium or a serum-containing medium. The growth of these cells is quite rapid in culture and inhibited in a dose-dependent manner by most teratogens thus far tested, such as dexamethasone. These cells are highly sensitive to a variety of DNA synthetic and mitotic inhibitors. The responses of these cells are complementary to the ovarian tumor cell attachment assay of Braun et al [1, and in this volume]. When used in conjunction with the tumor cells, the overall reliability is greater than 90% with only one false-negative, allopurinol.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0270-3211
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
2
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
313-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6130630-Cells, Cultured,
pubmed-meshheading:6130630-Dexamethasone,
pubmed-meshheading:6130630-Drug Evaluation, Preclinical,
pubmed-meshheading:6130630-Embryo, Mammalian,
pubmed-meshheading:6130630-Environmental Pollutants,
pubmed-meshheading:6130630-Female,
pubmed-meshheading:6130630-Humans,
pubmed-meshheading:6130630-Palate,
pubmed-meshheading:6130630-Pregnancy,
pubmed-meshheading:6130630-Teratogens
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pubmed:year |
1982
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pubmed:articleTitle |
Prescreening for environmental teratogens using cultured mesenchymal cells from the human embryonic palate.
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pubmed:publicationType |
Journal Article
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