Linked Life Data

6129867

Source:http://linkedlifedata.com/resource/pubmed/id/6129867

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9a
pubmed:dateCreated
1983-2-14
pubmed:abstractText
The results of a double-blind comparative study of a new antihistamine, alpha-[4-(1,1-dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1- piperidinebutanol (terfenadine, RMI 9918, Triludan, Teldane, resp.), are presented. Carried out on a total of 136 patients, this multicentre investigation had three main objectives: Firstly to evaluate the efficacy of terfenadine in skin allergies; secondly to evaluate its tolerance; and finally, to compare its activity with the activity of clemastine or with placebo. The results obtained with terfenadine are comparable to those obtained with the reference product clemastine and show that terfenadine is similar in efficacy to that expected when antihistamine drugs are used for the treatment of general allergic manifestations of skin. With respect to patient tolerance, the results are in agreement with those of previous studies which have demonstrated that terfenadine is well tolerated and that its sedative effect is negligible.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0004-4172
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1196-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Comparative study of terfenadine in allergic skin of patients in France.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial, Controlled Clinical Trial